1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE5-(Hydroxymethyl)furan-2-carbaldehydeCat. No.: HY-Y0051CAS No.: 67-47-0Synonyms: 2-Formyl-5-hydroxymethylfuran; 2-Hydroxymethyl-5-furfural分式: CHO分量: 126.11作靶點: Fungal作通路: Anti-infection儲存式: Pure form -20C 3 years4C 2 yearsIn sol

2、vent -80C 6 months-20C 1 month溶解性數據體外實驗 DMSO : 50 mg/mL (396.48 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 7.9296 mL 39.6479 mL 79.2959 mL5 mM 1.5859 mL 7.9296 mL 15.8592 mL10 mM 0.7930 mL 3.9648 mL 7.9296 mL請根據產品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和

3、期限。BIOLOGICAL ACTIVITY物活性 5-(Hydroxymethyl)furan-2-carbaldehyde，來質物質，能抑制酵母的長和發酵。IC50 & Target Yeast 1.體外研究It is found that furfural and HMF cause the attenuation of bulk translation activity and the assembly of1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEcytoplasmic mRNP granules in Saccharomyce

4、s cerevisiae. Notably, a combination of furfural and HMFinduce the remarkable repression of translation initiation and SG formation. Furfural and HMF can induce theformation of cytoplasmic mRNP granules, HMF also causes a gradual reduction in the polysome fraction anda concomitant increase in the 80

5、S monosome fraction 1.REFERENCES1. Iwaki A, et al. Biomass conversion inhibitors furfural and 5-hydroxymethylfurfural induce formation of messenger RNP granules andattenuate translation activity in Saccharomyces cerevisiae. Appl Environ Microbiol. 2013 Mar;79(5):1661-7.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-