1、Views & Comments大數據與精準醫學摘要：本文主要關注大數據分析對改善健康.預防和檢測早期 疾病以及個性化干預措施的潛在影響，討論了大數據分析在建 立患者電子健康檔案以獲得更好的臨床決策支持中的可能作用。 筆者研究了藥物遺傳學的發展，以更好地理解患者對化學療法 產生個同反應的原因。此外，筆者評估了在線健康交流的發展 以及如何利用這些數據檢測公共健康威脅和控制傳染病。最后, 筆者描述了新一代可穿戴和可植入的軀體傳感器如何改善身體 狀況、簡化慢性病管理和提高外科植入物質量。2018(CDSS)345 關St詞：大數據，生物傳感器，人體傳感網絡，可植入傳感器，臨床決策支持系統，藥物遺傳學

2、，移動醫療(ACL)712適用于精準醫學的大數據(EHR)()CYP2D68BRAF(Y472C)刃10H-13(Cancer Genom?Atlas)11(Cancer2Cell Line Encyclopedia)12(Genomics of Drug Sensitivityin Cancer)13The Hamn CGatro, South Konoington Campus, ImporolCollogG Loncton, London SW72AZ. UK* CorrecpondGocoauthor E-mait g.z.yanimpGrial.ac.ukThe Author(c)

3、2016 Pubfched by EnginGGringScisnooc Preco. The ican open accecoarticbundortheCC BY fcono(hnp：crootKwommoncorgfcGnby/4.0/) 英文原文：EnginoGring2016.1(3： 277-279 引用本文：Daniel Rchard Leff. GuongrZhong Yang Bq Data for Proccion fvtodicinG Engnnng, DOI 10.16302/J-ENG-2016076www.QnginGG Volume 1 Iosuq3 3GptGm

4、bGr2016 Engineeiing 265Views & Comments1420212220%23( )TuDiabetes(Boston Children Hospital)TuAnalyze 153結論16Ram)171917(EVD)18odium Compliance with ethics guidelinesDaniel Richard Leff and Guang-Zhong Yang declare that they have no conflict of interest or financial conflicts to discloseReferences1. J

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7、ly pio- phyiactic antibiotic adimni5tratx)n in suicical caes.Analg . 2010, 111(5):1293-1300266 EngiMeering Volumol Iocug3 Geptomber2015 www.onginGGViews & Comments5 K B. Wagholikar, et al. Clinical decision support xvith automated text pxo- cessuic for cervical cancer screenwc J Am Med. Infoim. Aaoc

8、. 2012, 19(5) S33-S396 J. futonia, J. Moms, J Luca A compaxison of niodek for predicting eady hospital reiidnuiom J Bicrnzd bjfoim, 2015, 56： 229-23S7. K Mei, J Peng, L Gao, N N Zheng, J Fan. Hieiaxchic&l classification of Urge- scale patient xecoids for automatic treatment strah&cabon. IEEE J Biomt

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10、0. T. Watanabe, T Kobuivu, T Akiyohi, K MaEuda, S khihara, K Nozawa Predac t)on of pome to preoptnhv* chenioxMliotiwxapy in xtcfal cancer by us u it vine haxccnptae polyiexae chain reaction analysis of foui genes Du Colon RBction, 2014,57(1)： 23-3111. Cancer Genonw Atlas Reseaich NeMork, J N. Wtrnst

11、em. tt al The Cunctr Gt- noxne Atks PaivCwcei analysu project ZAu Gewz., 2013, 4X10) 1113-112012. J. Banhna, et al The Cancer Cell Line Encyclopedia enables predictive modelling of anhcMrcx diu& stmihnty Nati, 2012,483(7391) 603-60713. M J. Gaxnett, etal Sptenutic ldexxhEcabon of genonnc nvuken of d

12、nig sensitivity m cancer cells Mwn-r. 2012.4S3(7391) 570-57514. J. Sheng, F Li, S T. Wang Optimal dxuc piedicbon from penoxul (enoxrac; profiles. 1EEEJ. Bi6Z Health b 血 rm, 2015,19(4)： 1264-127015. Ancn TuAiialyze is hexe! 2010-05-19 http /mtwit tudiabetes oig/foium/topie/ tuaralyae-is-heie16 S Ram,

13、 W Zhw, M VAIhams, Y Pengetna Predicting aittum-xthted emergexh cy department visit; nsing big data IEEE J. Btanvd. Health bjformy 2015, 19(4) 1214132317. M Odirnv S Yooa What canvre leant about the Ebola oufcitak from tvreet? Am J bct Comroi 2015.43(6) 563-571IS S BahkaU N AUdvujy, M Alowmniy, M Haaseh, O Davarv K Akunnu A social medu caiirp&icu to promote bre&5tfeehng among Saidi vromext A tv eb-based sur- veysfcidy 處以 Health Technol 加伽nt, 2015t 213 247-25019 G Z Yang Bo Sfruar Nttorkt 2n