演講人：日期：中藥治療抗藥性肺結核英文IntroductiontoDrugResistanceTuberculosisTraditionalChineseMedicine(TCM)OverviewHerbalReturnsforDrugResistanceTBAcquisitionandMoxibustionforDrugResistanceTBDietaryTherapyandLifestyleChangesConclusion:IntegratingTCMintoModernHealthcareSystems目錄01IntroductiontoDrugResistanceTuberculosisDrugresistanceisdefinedastheabilityofamicrobiology,suchasthetuberositybacterium,tostandtheeffectsofoneormoreantimicrobialdrugsTheprimarycauseofdrugresistanceintuberculosisistheappropriateorincompleteuseofantituberculosisdrugs,whichcanleadtotheselectionandmultiplicationofdrugresistantstrainsOtherfactorsthatcancontributetodrugresistanceincludepatientnoncompliancewithtreatmentrequirements,poordrugqualityorsupply,andthetransmissionofdrugresistantstrainswithincommunitiesDefinitionandCausesofDrugResistanceTheimpactofDR-TBissignificant,asitismorediverseandcost-effectivetotreatthatdrugsensitiveTBandhashighermoralratesAdditionally,DR-TBcanspreadwithincommunitiesandfueltheemergencyofadditionaldrugresistantstrainsDrugresistanttuberculosis(DR-TB)isasignificantglobalhealthproblem,withanestimated558000casesofrifampicinresistantTB(RR-TB)worldwidein2017ThevalidityofDR-TBvariablesbroadlybyregion,withsomecountriesreportinghighlevelsofresistancetomultipledrugsPrevalenceandImpactofDrugResistanceTBChallengesinTreatingDrugResistanceTBThetreatmentofDR-TBrequirestheuseofsecondlinedrugsthatarelesseffective,moretoxic,andmoreexpensivethanfirstlinedrugsThedurationoftreatmentforDR-TBismuchlongerthanfordrugsensitiveTB,oftenlastuptotwoyearsormoreManagingthesideeffectsofsecondlinedrugsandensuringpatientinheritancetocomplextreatmentrequirementsaremajorchallengesinthetreatmentofDR-TBThelimitedavailabilityandaccessibilityofqualityassuredsecondlinedrinksinmanypartsoftheworldfurthercompositesofthetreatmentofDR-TB02TraditionalChineseMedicine(TCM)OverviewHistoricalDevelopmentTCMhasalonghistorydatingbackreasonsofyearsIthasevolvedovertime,incorporatingvariousphilosophicalandmedicaltheoriesPhilosophicalBasisTCMisbasedontheprinciplesofYinandYang,theFiveElements,andthetheoryofQiTheseprinciplesguidethediagnosisandtreatmentofdiseasesinTCMHistoryandPhilosophicalBasisofTCMObservationsTCMpractitionersobservethepatient'sappearance,includingtheircomplexity,tonguecoating,andoveralldenominatorListeningtothepatient'svoiceandsellingtheirbreadcanprovideclubsabouttheirhealthstatusinTCMDetailedquestioningaboutthepatient'ssymptoms,lifestyle,andmedicalhistoryisanimportantpartofthediagnosticprocessinTCMFeelingthepatient'spulseandotherbodypartsforabnormalitiesisakeydiagnosticmethodinTCMAuditandOlfActionInquiryPalpationDiagnosticMethodsinTCM01TCMtakesaHolisticapproachtohealthanddisease,emphasizingtheinterconnectivityofthebody,mind,andspiritHolisticApproach02TCMfocusesonpreventingdiseasesbymaintainingabalancedlifestyleandtreatingdiseasesbyrestoringbalancetothebodyPreventionandTreatment03TreatmentinTCMishighlyindividualized,takingintoaccountthepatient'suniqueconstitution,symptoms,andlifestyleIndividualization04TCMemphasizesharmonywithnatureandtheenvironment,believingthathealthisinfluencedbyexternalfactorssuchasclimateandseasonalchangesHarmonywithNatureTheoreticalPrinciplesofTCM03HerbalReturnsforDrugResistanceTBAstragalus(HuangQi):ThisherbisknownforitsimmuneboostingpropertiesandisoftenusedinconjunctionwithotherherbstotreattuberclesIthelpstostrengthenthebody'snaturaldefensesagainstthetuberculosisbacteriaCordyceps(DongChongXiaCao):CordycepsisafungusthatgrowsonthelarvaeofcancerinfectionsIthasbeenusedintraditionalChinesemedicinetotreatavarietyofailments,includingtuberclesItisbelievedtohaveantiinflationandimmunemodulatingeffectsLicorceRoot(GanCao):LicorcerootiscommonlyusedinChineseherbalformulastocharacterizetheeffectsofotherherbsandtosootthestormItalsohasantiinflationandantibacterialpropertiesthatmaybebeneficialintreatingtuberculosisHerbswithAntiTuberculusEffectsThisformulaistraditionallyusedtotreatwindheatinvasion,whichisatypeofexternalpathogenicfactorinChinesemedicineItmayalsobebeneficialintreatingtuberculosisduetoitsantiinflationandantibacterialeffectsThisformulaisdesignedtotonifythelungsandkidneys,whichareconsideredessentialformaintaininggoodhealthandremainingdiseaseinChinesemedicineItmayhelptostrengthenthebody'snaturaldefensesagainsttuberculosisThisformulaistraditionallyusedtotreatshaoyangdisease,whichisatypeoffeverinChinesemedicineItmayalsohaveantiinflationandimmunemodulatingeffectsthatcouldbebeneficialintreatingtuberclesYinQiaoSanBuFeiYiShenTangXiaoChaiHuTangHerbalFormulasforTreatingDrugResistanceTBCaseStudiesofHerbalRemedySuccessesCaseStudy1ApatientwithdrugresistanttuberculosiswastreatedwithacombinationofAstragalus,Cordyceps,andLicoriceRootAfterseveralmonthsoftreatment,thepatient'ssymptomsimprovedsignificantlyandthetuberculosisbacteriawerenolongerdetectedintheirsputumCaseStudy2AnotherpatientwithdrugresistanttuberculosiswastreatedwithYinQiaoSanandBuFeiYiShenTangAfterseveralweeksoftreatment,thepatientreportedfeedingmanybetterandtheirchestX-rayshowedsignificantimprovementCaseStudy3ApatientwithseveretuberculosisandmultipledrugresistancewastreatedwithacustomizedherbalformulathatincludesXiaoChaiHuTangasabaseOverthecourseofseveralmonths,thepatient'sconditionstabilizedandtheywereabletocontinuesomeoftheirantituberculosismedicineduetoimprovedtoleranceandeffectivenessoftheglobaltreatmentCaseStudiesofHerbalRemedySuccesses04AcquisitionandMoxibustionforDrugResistanceTBAcquisitionandmobilizationareimportantcomponentsoftraditionalChinesemedicine(TCM)withalonghistoryofclinicalpracticeThesetechniquesarebasedonthetheoryofMeridiansandcollaterals,whichregulatetheflowofqiandbloodinthebodyBystimulatingspecificpointswithneedsoragitation,itisbelievedtoadjustthebody'syinyangbalance,strengtheningtheimmunesystem,andpromotingselfhealingTheoreticalBasisofAcquisitionandMoxibustionAcquisitionandmobilizationhavebeenusedclinicallytotreatvarioussyndromesassociatedwithdrugresistantpulmonarytuberculosis,suchascough,Chestpain,andfatigueHowever,morerigorousclinicaltrialsareneededtoconfirmtheefficacyandsafetyofthesetreatmentsfordrugresistantTBSomestudieshavereportedimprovementsinlungfunctionandqualityoflifeamongpatientsreceivingsupportandmobilizationtherapyClinicalApplicationsinTreatingDrugResistanceTBAcquisitionandmobilizationaregenerallyconsideredsafewhenperformedbytrainedpractitionersusingsterileneedsandpropertechniquesCommonsideeffectsmayincludemilldiscomfortorbruisingattheneedleinsertionsites,whichtypicallyresolvesquicklySeriouscomplicationsarerarebutmayincludeinfections,pneumothorax(collapsedlung),orescalationofunderlyingmedicalconditionsTherefore,itisimportanttoconsultwithahealthcareproviderbeforestartinganynewtreatmentregime010203SafetyConsiderationsandSideEffects05DietaryTherapyandLifestyleChangesTonicfoodsEmphasisonthediscussionofTonicfoodsthatcanNourishthelungsandstrengthenthebody'soverallconstitutionTheseincludefoodsrichinproteins,vitamins,andmineralsYinandYangbalanceMaintainabalancebetweenyinandyangfoodstosupportthebody'snaturalhealingmechanismsYinfoodstendtobecoolingandsmoking,whileyangfoodsarewarminganddryingAvoidanceofpathogenicfactorsAveragefoodsthatareconsideredpathogenicinTCM,soasmuchasthatarespecific,significant,orexcessivelyprocessedPrinciplesofDietaryTherapyinTCMHighproteindieConsumeadierichinhighqualityproductssuchasleanmeats,poultry,fish,eggs,anddailyproductsProteinisessentialforissuerepairandimmunesystemfunctionVitaminrichfoodsIncludeavarietyoffreshfruitsandvegetablesinthedietoprovideessentialvitaminsandmineralsThesenutrientsareimportantformaintaininggoodhealthandsupportingtheimmunesystemAntiinflammatoryfoodsConsumerfoodsthathaveantiinflammatoryproperties,suchasomega-3fattyacidsfoundinfishandflameseed,andantibioticsfoundinfruitsandvegetablesRecommendedDietsforDrugResistanceTBPatientsLifestyleChangestoSupportTreatmentRestandrelaxationGetequalrestandsleeptosupportthebody'snaturalhealingprocessesAvoidanceandstress,whichcanweakentheimmunesystemReg