1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEAstragaloside IICat. No.: HY-N0433CAS No.: 84676-89-1Synonyms: Astrasieversianin VIII分式: CHO分量: 827.01作靶點: Others作通路: Others儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數據體外實驗 DMSO : 100 mg/mL (120.92

2、 mM; Need ultrasonic)H2O : 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (3.02 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (3.02 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性芪皂苷II (Astragaloside II) 從 芪中分離到的種天然化合物。

3、REFERENCES1. Haijun Qu, et al. Quantification and pharmacokinetics of astragaloside II in rats by rapid liquid chromatography-tandem massspectrometry. Anal. Methods, 2014,6, 6815-68222. Kong XH, et al. Astragaloside II induces osteogenic activities of osteoblasts through the bone morphogenetic prote

4、in-2/MAPK andSmad1/5/8 pathways. Int J Mol Med. 2012 Jun;29(6):1090-8.3. Huang C, et al. Reversal of P-glycoprotein-mediated multidrug resistance of human hepatic cancer cells by Astragaloside II. J PharmPharmacol. 2012 Dec;64(12):1741-50.4. Wan CP, et al. Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity. ActaPharmacol Sin. 2013 Apr;34(4):522-30.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>