1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE5-Methyltetrahydrofolic acidCat. No.: HY-113046CAS No.: 134-35-0分式: CHNO分量: 459.46作靶點(diǎn): Endogenous Metabolite作通路: Metabolic Enzyme/Protease儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 83.

2、33 mg/mL (181.37 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.1765 mL 10.8823 mL 21.7647 mL5 mM 0.4353 mL 2.1765 mL 4.3529 mL10 mM 0.2176 mL 1.0882 mL 2.1765 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍福渲魄罢?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作

3、液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (4.53 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (4.53 mM); Clear solution3. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolu

4、bility: 2.08 mg/mL (4.53 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 5-Methyltetrahydrofolic acid種具有物活性的葉酸形式。5-Methyltetrahydrofolic acid是四氫葉酸的甲 化衍物。5-Methyltetrahydrofolic acid 主 的天然膳葉酸， 漿和腦脊液中葉酸的主要形式1。REFERENCES1. Wright AJ, et al. Comparison of (6 S)

5、-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietaryintervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-weekplacebo-controlled study in healthy adults. Br J Nutr. 2010 Mar;103(5):724-9.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 02