MedicalBiochemistry知到智慧樹期末考試答案題庫2025年溫州醫科大學Xerodermapigmentosumresultsfromadeficiencyin（）

答案:DNArepairXerodermapigmentosum(xp)resultsfromadeficiencyin_____.（）

答案:DNArepairWhichtypeofthefollowinghistonesisnotacomponentinthecoreparticlesofthenucleosome?（）

答案:H1WhichstatementabouttheCoricycleisTRUE?（）

答案:Lactateisproducedbyskeletalmuscleandtransportedtotheliverwhereitisutilizedasagluconeogenicsubstrate.Whichsetofaminoacidscanabsorb280nmUVlight?（）

答案:Trp&TyrWhichproteinlevelwillobviouslydecreasebecauseoftheliverdamage?（）

答案:AlbuminWhichpathwayofthefollowingisrelatedtonucleicacidssynthesis?（）

答案:PentosephosphatepathwayWhichorganelleinthehepatocytesdotheconjugationofbilirubininhumanbody?（）

答案:smoothendoplasmicreticulumWhichoneofthefollowingvitaminsisinvolvedinbloodclotting?（）

答案:VitaminKWhichoneofthefollowingstatementsiswrong?（）

答案:Thebodycansynthesizealltheaminoacidsthatmakeupproteins.Whichoneofthefollowingproteinshasquaternarystructure?（）

答案:HemoglobinWhichoneofthefollowingnucleotideisthefirstnucleotideindenovosynthesispathwayofpurinenucleotide?（）

答案:IMPWhichoneofthefollowingistrueaboutdenaturedproteins?（）

答案:Biologicalactivitydecreases.WhichoneofthefollowingenzymesdeficiencycanleadtoLesch-Nyhansyndrome?（）

答案:HGPRTWhichoneofthefollowingdoesnotoccursinthedegradationpathwayofAMP?（）

答案:TheendproductisCOWhichoneofthefollowingcompoundsdoesnotparticipateinthesynthesisofpyrimidinenucleotide?（）.

答案:GlycineWhichoneofthefollowingaminoacidscontainahydroxylgroup？（）

答案:TyrosineWhichoneofthefollowingaminoacidisinvolvedinthesynthesisofnucleotide?（）.

答案:GlutamineWhichonecanconformtothestructuralfeaturesoftRNA?（）

答案:AnticodonWhichofthefollowingvitaminscontainsthemetalcobaltatom？（）

答案:VitB12Whichofthefollowingvitamindeficienciescausesnightblindness?（）

答案:VitAWhichofthefollowingvitamindeficienciescancauseberiberi?（）

答案:VitaminB1Whichofthefollowingsubstancedirectlylinksnucleotidesynthesisandglucosemetabolism?（）。

答案:Ribose-5-phosphateWhichofthefollowingstepsisNOTincludedintheproteinbiosynthesis?（）

答案:Post-transcrptionalprocessingWhichofthefollowingstatementsmostcloselydescribesthephenomenonofuncouplinginoxidativephosphorylation?（）

答案:ATPformationceases,butoxygenconsumptioncontinuesWhichofthefollowingstatementsiscorrectaboutprokaryoticgeneexpression?（）

答案:ProkaryoticmRNAsareoftentranslatedbeforetranscriptioniscomplete.Whichofthefollowingstatementsaboutvitaminsiswrong?（）.

答案:Themainfunctionofvitaminsistoprovideenergythroughoxidation.Whichofthefollowingstatementsaboutnucleosomestructureiscorrect?（）

答案:NucleosomespermitefficientpackingofDNAtoaboutoneseventhitsnormalvolume.Whichofthefollowingstateispositivenitrogenbalance?（）

答案:pregnantwomenWhichofthefollowingsequencesiscomplementarytotheDNAsequence5'-AAGTCCGA-3'?（）

答案:3'-TTCAGGCT-5'Whichofthefollowingreactionsisthemostcommonconjugationintheliver?（）

答案:Conjugation

with

glucuronic

acidWhichofthefollowingmetabolismdoesnotrequireNADPH?（）

答案:OxidationthroughtherespiratorychainWhichofthefollowingistheproductofRNA-polⅡ？（）

答案:hnRNAWhichofthefollowingisthecommonmaterialforthesynthesisofpyrimidineandpurinenucleotide?（）。

答案:GlutamineWhichofthefollowingisNOTtrueoftheprokaryotic(E.coli)transcriptionalprocess?（）

答案:AseparatehelicaseenzymeisnecessaryforunwindingtheDNAtemplatetocreateanopencomplex.Whichofthefollowingisnotthedirectmaterialofdenovosynthesisofpurinenucleotide?（）.

答案:GlutamateWhichofthefollowingisnottheactingpropertyofaminoacyl-tRNAsynthetase?（）

答案:catalyzingaminoacidbindingtothe5'-endoftRNAWhichofthefollowingisnotaphysiologicalroleofnucleotide?（）。

答案:componentsofmanyproteinsWhichofthefollowingisketogenicaminoacidonly?（）

答案:LeucineWhichofthefollowingisanintermediateinketonebodysynthesis?（）

答案:3-hydroxy-3-methylglutaryl-CoAWhichofthefollowingisamajorgluconeogenicsubstrate?（）

答案:alanineWhichofthefollowinghormonescanlowerbloodglucose？（）

答案:insulinWhichofthefollowingenzymesistheimportantregulatorypointinthebeta-oxidationoffattyacids?（）

答案:carnitineacyltransferaseIWhichofthefollowingenzymescatalyzestheratecontrollingstepinfattyacidbiosynthesis?（）

答案:acetyl-CoAcarboxylaseWhichofthefollowingenzymeistherate-limitingenzymeintheprocessofbileacidssynthesis?（）

答案:7α-hydroxylationWhichofthefollowingDOESNOTplayaroleinprokaryoticreplication?（）

答案:reversetranscriptaseWhichofthefollowingdescriptionsofglycogeninNOTtrue?（）

答案:glycogenisdegradedstartingatthereducingend.Whichofthefollowingcompoundsisnotdirectlyinvolvedinthecitricacidcycle?（）

答案:PyruvateWhichofthefollowingcomponentsofthemitochondrialelectrontransportsystemareincapableofcarrying2electrons?（）

答案:cytochromeCWhichofthefollowingcanresultsintheframeshiftmutationofDNA?（）

答案:thedeletionofonebaseinDNAWhichofthefollowingaminoacidsisinvolvedintheformationofdisulfidebridge?（）

答案:CysteineWhichofthefollowingaminoacidresiduescanbephosphorylated?（）

答案:SerWhichoffollowingvitaminscanbeconvertedintoNAD+andNADP+?（）

答案:VitPPWhichfollowingcanfeedbackinhibitALAsynthase?（）

答案:HemeWhichcoenzymeinpyruvatedehydrogenasecomplexservesasthefinalhydrogensacceptor?（）

答案:NAD+Whichbilepigmentcaneasilygothroughthebiomembrane?（）

答案:FreebilirubinWhen[S]=4Km,thevelocityoftheenzymaticreactionisabout（）.

答案:0.8VmaxWhat‘sthematerialsofhemesynthesis?（）

答案:glycine,succinylCoA,Fe2+Whatistherate-limitingenzymeintheprocessofhemesynthesis?（）

答案:ALAsynthaseWhatisthemaintransportationformofbilirubininserum?（）

答案:Bilirubin-AlbuminWhatisthefunctionofthe3'to5'exonucleaseactivityofbacterialDNApolymerases?（）

答案:removesmismatchedbasesduringreplicationWhatisthefecalcolorofthepatientswithobstructivejaundice?（）

答案:Kaolin-likecolorWhatistheenzymecatalyzed2,3-BPGtoform2,3-BPG?（）

答案:BisphosphoglycerasemutaseWhatdothedailybilirubinformationderivemainlyfrom?（）

答案:hemoglobinUnconjugatedbilirubincanbesecretedintotheurineinourbodies.（）

答案:錯Thevitaminthatcanbeconvertedfromcholesterolinthebodyis（）.

答案:VitaminDTheutilizationofketonebodieswouldoccurinallofthefollowingtissuesEXCEPT（）

答案:liver.Theuncouplingofoxidativephosphorylationfoundinthebrownfatmitochondriaofanewborninfantmightbeofphysiologicalimportancebecause（）

答案:itproducedheat.Thetypeofnucleicacidthatusuallycontainssmallquantitiesofavarietyofmodifiedribonucleotides,suchaspseudouridineandinosine,is（）.

答案:transferRNA.ThetertiarystructureoftRNAis（）.

答案:invertedLshapeThetemplatestrandofDNAis5’-ATTCAG-3’,itstranscriptis（）

答案:5’-CUGAAU-3’TheTATAboxineukaryotesisa_____.（）

答案:corepromoter.Thespecificityofenzymeisdeterminedby（）

答案:apoproteinThesequenceofoneDNAstrandisATGCAA,thecomplementarystrandofDNAis（）

答案:TTGCATThesequenceofnucleotideofinitiationcodenis（）

答案:AUGThereductionofwhichofthefollowingsubstancesproducesdeoxyribonucleotides?（）

答案:NDPTheproton-motiveforcegeneratedbytheelectrontransferchain（）

答案:hasalloftheabovecharacteristicsTheprincipalnitrogenousurinaryexcretionproductinhumansresultingfromthecatabolismofAMPis（）

答案:uricacidTheprimaryfunctionoftheureacycleis（）

答案:toconverttoxicammoniatoureawhichcanbeexcretedTheprecursorofeukaryoticmaturemRNA?（）

答案:hnRNAThephysiologicalsignificanceofzymogenactivationis（）

答案:toavoidself-damageThephenomenonwhichasingleaminoacidiscodedforbyseveraldifferenttripletcodonsiscalled（）ofgeneticcodons.

答案:degeneracyThenitrogensinureaoriginateMOSTDIRECTLY(fewestnumberofsteps)from（）

答案:carbamoylphosphateandaspartateThemRNAsequence:(5’)AAUGCAGCUUUAGCA(3’)andthesequenceofthecodingstrandis____.（）

答案:(5’)AATGCAGCTTTAGCA(3’)Themostsignificanceofbiotransformationisto（）

答案:Increasethesolubilityofthenon-nutritionalsubstanceandeliminatefromthebodyThemostimportantkeyenzymeinglycolysisis（）.

答案:phosphofructokinase-1Themostimportantchemicalbondthatmaintainaprotein'sprimarystructureis（）.

答案:saltbondThemostcommondonorofmethylgroupsinbiosyntheticreactionsis（）

答案:S-adenosylmethionine(SAM)ThemitochondrialelectrontransportsystemresponsibleforreoxidationofNADHandelectrontransfertooxygenislocatedininnermembraneofthemitochondria.（）

答案:對ThemaximalabsorptionpeakofnucleicacidtoUVlightisat（）

答案:260nmThemajorityofenergyformuscularcontractionisstoredinmuscletissueintheformof（）

答案:CreatinephosphateThemainstorgeformofironinthebodyis（）

答案:ferroproteinThemainfunctionoftheglycerolphosphateshuttleisin（）

答案:thetransportofreducingequivalentsintomitochondriafromNADHformedduringglycolysis.Thelipoproteinparticlesthathavethehighestpercentconcentrationoftriglycerideandthelowestdensityare（）

答案:thechylomicron.ThegeneexpressioncanberegulatedatthefollowinglevelsEXCEPT（）

答案:DNAreplicationTheformationofproteinsecondarystructureismainlydependenton（）

答案:hydrogenbondTheenzymeinchargeofproofreadingfunctioninDNAreplicationis（）

答案:DNApolymeraseTheeffectofnon-competitiveinhibitoronenzyme-catalyzedvelocityis（）

答案:Kmunchanged,VmaxdecreasedTheeffectofcompetitiveinhibitoronenzyme-catalyzedvelocityis（）.

答案:Kmincreased,VmaxunchangedThedirectionofproteinsynthesis(polypeptidechain)is（）

答案:FromNtoCThedirectprecursorofdTMPsynthesisis（）.

答案:dUMPThedirectdonorofglucosylgroupinglycogenesisis（）.

答案:UDPGTheconceptof"wobble"involves_____.（）

答案:basepairingbetweenthethirdbaseofthecodonandthefirstbaseoftheanticodon.Thecoenzymeofpyruvatecarboxylaseis（）.

答案:biotinThecoenzymeofALAsynthaseistheactiveformof（）

答案:VitB6ThecodoninmRNAreverselycomplementarypairingwithanti-codonUGCintRNAis（）

答案:GCAThecitricacidcycleisinitiatedbythecondensationoftwomolecules,whichare（）.

答案:acetyl-CoAandoxaloacetateThechemiosmotichypothesisforoxidativephosphorylationproposesthatthedrivingforcefortheformationofATPis（）

答案:aprotongradientacrossthemitochondrialmembraneThecauseofthebilirubinintheurineis（）

答案:IncreaseoftheconjugatedbilirubininthebloodThebilirubinissparinglysolubleinplasmaandwater.（）

答案:對ThebasesofRNAarethesameasthoseofDNAwiththeexceptionthatRNAcontains（）.

答案:uracilinsteadofthymineThebaseisfoundinmRNAbutnotinDNAis（）

答案:UThearrangementofatomsonthebackboneofthepolypeptidechaincanbeexpressedas（）.

答案:-C-N-C-C-Theaminoacidwhichdoesnotexistinnaturalproteinsis（）

答案:citrullineTheaminoacidthatisinvolvedinalmosteveryaminotransferasereactionis（）

答案:glutamateTheactiveformofvitaminDinthebodyis（）

答案:1,25-(OH)2-vitaminD3TheactiveformofvitaminAinrhodopsinis（）.

答案:11-cisretinalTheAAUAAAsequenceonaRNAmoleculemarks_____.（）

答案:Thesitenearwhichtheprimarytranscriptiscleavedandapoly(A)sequenceisadded.The5′endofmRNAinmosteukaryoteshas（）

答案:CapstructureSulfadrugssuchassulfanilamideareeffectiveagainstcertainpathogenicbacteriabecause（）.

答案:theyblockthesynthesisoffolate.Substratelevelphosphorylationoccursinwhichofthefollowingreactions?（）

答案:Succinyl-CoA→succinateRNApolymeraseisboundinitiallyto_____ofanoperon?（）

答案:PromoterRegardingtheprocessofDNAreplicationinE.coliwhichofthefollowingstatementsisWRONG?（）

答案:DNAreplicationisunidirectional.Reasonthatmatureerythrocyterelyonglycolysisforenergyis（）inthecells.

答案:nomitochondriaPyridoxalphosphateactsascoenzymeinmost（）

答案:transaminationreactions.Promoterisdefinedas（）

答案:aregionofDNAtemplatewhichRNA-polbindstoProcessingofatRNAmoleculeincludesallofthefollowingEXCEPT（）

答案:removalofintronsbyspliceosomesPost-translationalmodificationsofpolypeptidesincludeallthefollowingEXCEPT（）.

答案:cappingby7-methylguanidinePost-translationalmodificationsofpolypeptidesincludeallthefollowingEXCEPT_____?（）

答案:cappingby7-methylguanidinePeptidyltransferase_____.（）

答案:isanintrinsicenzymaticactivityofthelargeribosomalsubunitandrequiresanRNAcomponent.Okazakifragmentsare（）

答案:foundonthelaggingstrandOkazakifragmentsare_____.（）

答案:foundonthelaggingstrand.Obstructionofthecommonbileduct,withtheresultinglossofbilesaltsforemulsificationwouldbeexpectedtoimpairabsorptionofallofthefollowingEXCEPT（）

答案:vitaminCNottakingintoaccounttheNADHgeneratedinthemalatedehydrogenasereaction,howmanyhigh-energyphosphatebondsareusedtoformamoleculeofurea,startingfromammoniaandHCO3-?（）

答案:4Muscleglycogencannotreplenishbloodsugarbecausemusclecellslack（）

答案:glucose-6-phosphataseMobilizationoffatfromadiposetissuerequirestheenzymaticactivityof（）

答案:hormone-sensitivelipase.Isoenzymesarebestdefinedas（）

答案:severalenzymesfromasinglespeciescatalyzingthesamereaction.IndicatewhichofthefollowingeventscanoccurduringtheprocessingofeukaryoticmRNAtranscripts.（）

答案:Excisionsofintrons.Indicatethecorrectsequenceofreactionsemployedforbeta-oxidationofacyl-CoAderivativesfromthelistbelow.（）

答案:oxidationcoupledtoFAD,hydration,oxidationcoupledtoNAD,thiolysisInthereplicationofeukaryoticDNA,（）

答案:theleadingstrandissynthesizedinthedirectiontakenbythereplicationfork.Intheenterohepaticcirculationonlyalittlefractionofbileacidsarereabsorbedintheintestine.（）

答案:錯Intheelectrontransportschemebelow,whichelectroncarrierismissing?（）NADHFMNH2?cytochromesO2

答案:UbiquinoneInseveralcodonsforencodingidenticalaminoacid,thespecificityofaminoacidisdeterminedby（）.

答案:thefirstandsecondbasesInRNApolymeraseofE.coli,thesubunitwhichcanrecognizetheoriginoftranscriptionis（）.

答案:σsubunitInproteinsynthesis,theinitiation(start)codoninmRNAis（）.

答案:AUGIftheenzymaticvelocityis90%ofVmax,[S]shouldbe（）timesofKm.

答案:9Ifthecontentofadenineis15%inaDNAdoublehelix,thatofcytosineis（）

答案:35%IfthecodenofmRNAisACG,thentheanticodenoftRNAis（）

答案:CGUIfthebasesequenceinafragmentofthecodingstrandofDNAis5′-ACTACTCAG-3′,correspondingsequenceofmRNAproducedbytranscriptionis（）.

答案:5′-CUGAGUAGU-3′Howmanyoxygenscanamoleculeofhemoglobinbind?（）

答案:4HowmanymoleculesofATPareproducedbythecompleteoxidationofoneacetylCoAthroughthecitricacidcycle?（）

答案:10HMGCoAcanactasaprecursorforallofthefollowingEXCEPT:（）

答案:lecithin.HighenergycompoundsincludeallofthefollowingEXCEPT（）

答案:AMPGluconeogenesistakesplacepredominantlyin（）.

答案:liverFortransportacrosstheinnermitochondrialmembrane,longchainfattyacidsareattachedto（）

答案:carnitine.Folatedeficiencycancause（）

答案:megaloblasticanemiaFMNistheactiveformof（）.

答案:RiboflavinFattyacidsfromadiposetissuearetransportedtositesofutilizationintheformof（）

答案:freefattyacidsboundtoserumalbumin.Exportofacetyl-CoAfrommitochondriatocytosoltoparticipateinfattyacidorsteroidbiosynthesisinvolves（）

答案:transportofcitratefrommitochondria.Essentialofproteindenaturationis（）

答案:breakofnon-covalentbondsEnzymesdoallofthefollowingEXCEPT（）

答案:altertheequilibriumconstantofareaction.DuringeukaryoticDNAreplication