藥劑英文試題及答案

一、單項選擇題（每題2分，共20分）1.Theterm“pharmaceutics”refersto（）A.ThestudyofdrugactionB.ThescienceofdosageformdesignandpreparationC.ThestudyofdrugmetabolismD.Thestudyofdrugdistribution答案：B2.Whichofthefollowingisasoliddosageform?（）A.SolutionB.EmulsionC.TabletD.Injection答案：C3.Themainfunctionofadisintegrantinatabletisto（）A.BindthepowdertogetherB.ImprovetheappearanceofthetabletC.PromotethebreakupofthetabletinthebodyD.Preventthetabletfrombreaking答案：C4.Theabbreviation“IV”inpharmaceuticaladministrationmeans（）A.IntramuscularinjectionB.IntravenousinjectionC.OraladministrationD.Subcutaneousinjection答案：B5.Theprocessofconvertingadrugfromasolidstatetoaliquidstatebyheatingiscalled（）A.DissolutionB.MeltingC.EvaporationD.Crystallization答案：B6.Asurfactantisasubstancethatcan（）A.IncreasethesurfacetensionofaliquidB.DecreasethesurfacetensionofaliquidC.IncreasetheviscosityofaliquidD.Decreasetheviscosityofaliquid答案：B7.Whichofthefollowingisanaturalpolymerusedinpharmaceuticalformulations?（）A.PolyethyleneglycolB.GelatinC.PolyvinylalcoholD.Polystyrene答案：B8.Thepurposeofcoatingatabletisnotto（）A.MaskthetasteofthedrugB.ProtectthedrugfromdegradationC.IncreasethedrugreleaserateD.Improvetheappearanceofthetablet答案：C9.Thesolubilityofadruginasolventismainlyaffectedby（）A.ThecolorofthedrugB.TheshapeofthedrugparticlesC.ThetemperatureandpolarityofthesolventD.Thesizeofthecontainer答案：C10.Anemulsionisasystemconsistingof（）A.TwoimmiscibleliquidsB.AsolidandaliquidC.TwomiscibleliquidsD.Agasandaliquid答案：A二、多項選擇題（每題2分，共20分）1.Whichofthefollowingaredosageforms?（）A.CapsulesB.SyrupsC.SuppositoriesD.Aerosols答案：ABCD2.Thefactorsaffectingdrugdissolutionrateinclude（）A.ParticlesizeofthedrugB.TemperatureC.StirringspeedD.Solubilityofthedrug答案：ABCD3.Commonlyusedexcipientsintabletformulationsare（）A.FillersB.LubricantsC.BindersD.Disintegrants答案：ABCD4.Whichofthefollowingareparenteraladministrationroutes?（）A.IntramuscularinjectionB.SubcutaneousinjectionC.IntravenousinjectionD.Intradermalinjection答案：ABCD5.Thefunctionsofapreservativeinaliquidformulationare（）A.PreventmicrobialgrowthB.KeeptheformulationstableC.ImprovethetasteD.Enhancethedrugsolubility答案：AB6.Examplesofsemi-soliddosageformsare（）A.OintmentsB.CreamsC.GelsD.Pastes答案：ABCD7.Thecharacteristicsofanidealdrugcarrierinclude（）A.BiocompatibilityB.Gooddrug-loadingcapacityC.ControllabledrugreleaseD.Easytoprepare答案：ABCD8.Factorstoconsiderwhenchoosingasolventforadrugsolutionare（）A.SolubilityofthedrugB.ToxicityofthesolventC.CostofthesolventD.Volatilityofthesolvent答案：ABCD9.Whichofthefollowingcanbeusedasemulsifyingagents?（）A.NaturalgumsB.SurfactantsC.ProteinsD.Polymers答案：ABCD10.Thepurposesofdrugformulationdesignare（）A.ImprovedrugstabilityB.EnhancedrugefficacyC.ReducedrugtoxicityD.Improvepatientcompliance答案：ABCD三、判斷題（每題2分，共20分）1.Asolutionisahomogeneousmixtureofasoluteandasolvent.（）答案：對2.Enteric-coatedtabletsaredesignedtoreleasethedruginthestomach.（）答案：錯3.Thelargertheparticlesizeofadrug,thefasteritsdissolutionrate.（）答案：錯4.Suspensionsarestablesystemswithuniformdistributionofsolidparticlesinaliquid.（）答案：錯5.Intravenousinjectionisarapidandeffectivewaytodeliverdrugsintothebody.（）答案：對6.Alubricantinatabletformulationhelpstopreventthetabletfromstickingtothedie.（）答案：對7.Thesolubilityofadruginwaterisalwaysthesameregardlessoftemperature.（）答案：錯8.Emulsionscanbeusedtoimprovethestabilityandbioavailabilityofsomedrugs.（）答案：對9.Allpolymersusedinpharmaceuticalsaresynthetic.（）答案：錯10.Themainroleofafillerinatabletistoprovidebulktothetablet.（）答案：對四、簡答題（每題5分，共20分）1.Whatistheimportanceofdrugformulation?答案：Drugformulationcanimprovedrugstability,enhanceefficacy,reducetoxicity,andincreasepatientcompliance.Ithelpsconvertdrugsintosuitabledosageformsfordifferentadministrationroutesandbetterdrugperformanceinthebody.2.Listtwomethodstoincreasethesolubilityofapoorlysolubledrug.答案：Onemethodistoreducetheparticlesizeofthedrugtoincreaseitssurfacearea.Anotheristouseaco-solventorasolubilizingagenttochangethesolventenvironmentandenhancedrugsolubility.3.Whatarethefunctionsofabinderintabletmanufacturing?答案：Abinderintabletmanufacturingbindsthepowderingredientstogether.Ithelpsformacohesivemassduringcompression,ensuringthetabletsmaintaintheirshapeandintegrity,andpreventingthemfromcrumbling.4.Explaintheconceptofcontrolled-releasedosageforms.答案：Controlled-releasedosageformsaredesignedtoreleasedrugsatapredeterminedrateoveranextendedperiod.Thiscanmaintainastabledrugconcentrationinthebody,reducedosingfrequency,andimprovepatientconvenienceanddrugefficacy.五、討論題（每題5分，共20分）1.Discusstheadvantagesanddisadvantagesoforaladministrationcomparedtoparenteraladministration.答案：Advantagesoforaladministrationincludeconvenience,patientacceptance,andlowercost.Butitmayhavelowbioavailabilityduetofirst-passmetabolismandvariableabsorption.Parenteraladministrationisrapidandreliable,butit'sinvasive,requirestrainedstaff,andhashigherriskslikeinfection.2.Howtoensurethestabilityofaliquidpharmaceuticalformulation?答案：Useappropriatepreservativestopreventmicrobialgrowth.AdjustthepHtoanoptimalrange.Selectstablesolventsandadditives.Protectfromlight,heat,andhumidity.Conductstabilitystudiestodetermineshelf-lifeandstorageconditions.3.Analyzethekeyfac