1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemELuteolinCat. No.: HY-N0162CAS No.: 491-70-3Synonyms: Luteolol; Digitoflavone; Luteoline分式: CHO分量: 286.24作靶點: Autophagy; Mitophagy作通路: Autophagy儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數據體外實驗 DMSO

2、: 100 mg/mL (349.36 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.4936 mL 17.4679 mL 34.9357 mL5 mM 0.6987 mL 3.4936 mL 6.9871 mL10 mM 0.3494 mL 1.7468 mL 3.4936 mL請根據產品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內實驗 請根據您的實驗動物和給藥式選擇適當的溶解案，配制前請先配制澄清的儲備液，再

3、依次添加助溶劑(為保證實驗結果的可靠性，體內實驗的作液，建議您現現配，當天使；澄清的儲備液可以根據儲存條件，適當保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (8.73 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (8.73 mM); Clear solution1/2 Master of S

4、mall Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 Luteolin (Luteolol)種天然 酮類化合物，在抗癌 具有常重要的潛能。戶使本產品發表的科研獻 Front Pharmacol. 2018 Jun 13;9:620.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Liping Ma, et al. Luteolin exerts an anticancer effect on NCI-H460 human non-small c

5、ell lung cancer cells through the induction of Sirt1-mediated apoptosis. Molecular MedicineReports, 2015, 12 (3): 4196-42022. Su Bog Yee, et al. Growth inhibition of luteolin on HepG2 cells is induced via p53 and Fas/Fas-ligand besides the TGF- pathway.International Journal of Oncology, 2015, 47 (2)

6、: 747-7543. Pang Tao, et al. Effect of Luteolin on the Improvement of Cancerous Cachexia in Model Mice. China Pharmacy, 2015-074. Divyashree Ravishankar, et al. Exploring quercetin and luteolin derivatives as antiangiogenic agents. European Journal of MedicinalChemistryVolume 97, 5 June 2015, Pages 259274McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 40