Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEN-Acetyl-D-glucosamine-d3Cat.No.:HY-A0132S14CASNo.:77369-11-0Synonyms:N-Acetyl-2-amino-2-deoxy-D-glucose-d3分?式:C?H??D?NO?分?量:224.23作?靶點:Isotope-LabeledCompounds;EndogenousMetabolite;DrugDerivative;InterleukinRelated;DrugIsomer作?通路:Others;MetabolicEnzyme/Protease;Immunology/Inflammation儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性N-Acetyl-D-glucosamine-d3(N-Acetyl-2-amino-2-deoxy-D-glucose-d3)氘代標記的N-Acetyl-D-glucosamine.N-Acetyl-D-Glucosamine(N-Acetyl-2-amino-2-deoxy-D-glucose)N-?酰葡萄糖胺的D異構體，?種具有?服活性的葡萄糖單糖衍?物，具有抗腫瘤和抗炎特性。N-Acetyl-D-Glucosamine也細Escherichiacoli。N-Acetyl-D-Glucosamine可誘導Candidaalbicans中酵母-絲轉化。N-Acetyl-D-Glucosamine還能促進兔軟?損傷的愈合[1][2][3]。體外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattentionbecauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.REFERENCES[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-216.[2].SimonettiN,etal.Yeast-mycelialconversioninducedbyN-acetyl-D-glucosamineinCandidaalbicans.Nature.1974Jul26;250(464):344-6.[3].MasudaS,etal.Anti-tumorpropertiesoforallyadministeredglucosamineandN-acetyl-D-glucosamineoligomersinamousemodel.CarbohydrPolym.2014Oct13;111:783-7.[4].TamaiY,etal.EnhancedhealingofcartilaginousinjuriesbyN-acetyl-d-glucosamineandglucuronicacid[J].CarbohydratePolymers,2003,54(2):251-262.1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEMcePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3