Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEFlorfenicol-13C6Cat.No.:HY-B1374S2Synonyms:SCH-25298-13C6分?式:C???C?H??Cl?FNO?S分?量:364.17作?靶點:Isotope-LabeledCompounds;Bacterial;Antibiotic作?通路:Others;Anti-infection儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Florfenicol-13C6(SCH-25298-13C6)13C標記的Florfenicol.Florfenicol((-)-Florfenicol)?種?服有效的?譜抑抗?素，具有抗炎、促細胞凋亡、調節免疫反應等功能。體外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattentionbecauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.REFERENCES[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-216.[2].HuD,etal.Florfenicol-inducedMitochondrialDysfunctionSuppressesCellProliferationandAutophagyinFibroblasts.SciRep.2017Oct19;7(1):13554.[3].ArslanP,etal.InvitroeffectsoferythromycinandflorfenicolonprimarycelllinesofUniocrassusandCyprinuscarpio.EnvironSciPollutResInt.2021Sep;28(35):48408-48416.[4].Al-ShahraniS,etal.Florfenicolinducesearlyembryonicdeathineggscollectedfromtreatedhens.BMCVetRes.2015Aug18;11:213.[5].WangX,etal.Florfenicolinducedrenalinflammatoryresponseandapoptosisviacelladhesionmoleculessignalingpathway.PoultSci.2022Nov;101(11):102152.[6].LisM,etal.Modulationoflymphocytesubsetsandhumoralimmuneresponsebyflorfenicoladministeredtosheepredbloodcell-immunizedbroilerchickens.PolJVetSci.2019Dec;22(4):481-487.[7].XinxinC,etal.Florfenicolinhibitsallergicairwayinflammationinmicebyp38MAPK-mediatedphosphorylationofGATA3.ClinImmunol.2011Feb;138(2):231-8.[8].ShuangG,etal.Immunosuppressiveactivityofflorfenicolontheimmuneresponsesinmice.ImmunolInvest.2011;40(4):356-66.1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEMcePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly