山梨酸對斷奶仔豬生產性能的影響及其分子機制的綜述報告山梨酸對斷奶仔豬生產性能的影響及其分子機制的綜述報告摘要：山梨酸是一種植物中普遍存在的天然有機酸，已經廣泛地應用于豬飼料中。本文綜述了山梨酸對斷奶仔豬生產性能的影響及其分子機制并提出了進一步的研究方向和展望。研究發現，適當地加入山梨酸可以提高斷奶仔豬的生長性能、飼料利用率，改善養殖環境下的健康狀態和免疫功能，并緩解飼料資源的壓力。此外，山梨酸還能夠降低仔豬的腹瀉率和死亡率，提高養殖收益。實驗結果表明，山梨酸對斷奶仔豬的生長性能和飼料利用率的提高是由于其促進食物消化和吸收，增強腸道健康和免疫功能的作用所致。關鍵詞：山梨酸，斷奶仔豬，生產性能，分子機制IntroductionWiththeincreasingdemandforanimalproducts,intensiveanimalproductionhasbecomethemainmodeofanimalhusbandry.Asaresult,thepressureonfeedresourcesisbecomingmoreandmoreserious.Therefore,improvingthefeedutilizationefficiencyisoneoftheimportantmeanstoimprovetheproductivityandeconomicbenefitofanimalhusbandry.Organicacidsarewidelyusedinanimalhusbandrybecauseoftheirgoodacidifyingeffect,bacteriostasisandantioxidantproperties.Amongthem,malicacidisanaturalorganicacidcommonlyfoundinplants,whichhasmanyphysiologicalfunctions,suchasstimulatingthesecretionofdigestiveenzymesandimprovingthehealthofthedigestivesystem.Inthepastfewyears,researchershaveconductedalotofstudiesontheeffectofmalicacidonthegrowthperformanceofweanedpiglets,andhavemadesomeprogressinunderstandingitsmolecularmechanism.Inthispaper,wewillreviewtheeffectofmalicacidontheproductionperformanceofweanedpigletsanditsmolecularmechanism,andputforwardtheresearchdirectionandprospectinthefuture.EffectsofMalicAcidonGrowthPerformanceandFeedUtilizationofWeanedPigletsInrecentyears,alargenumberofstudieshaveshownthatappropriateadditionofmalicacidinthedietofweanedpigletscanimprovethegrowthperformanceandfeedutilizationrateofpiglets,reducetheoccurrenceofdiarrheaandmortality,andimprovethehealthstatusandimmunefunctionofpiglets.Studieshaveshownthattheadditionofmalicacidtoweanedpiglets'dietscansignificantlyincreasetheaveragedailygain(ADG)andaveragedailyfeedintake(ADFI),andreducethefeed/gainratio(F/G)ofweanedpiglets.Thisindicatesthatmalicacidhasacertainpromotingeffectonthegrowthperformanceandfeedutilizationofweanedpiglets.Themechanismofactionisrelatedtotheimprovementofdigestivefunctionandtheregulationoftheintestinalmicroflora.EffectsofMalicAcidonHealthStatusandImmuneFunctionofWeanedPigletsStudieshaveshownthattheappropriateadditionofmalicacidtothedietofweanedpigletscanimprovethehealthstatusandimmunefunctionofpiglets.Intheprocessofweaning,thepiglets'digestivesystemandimmunesystemareundergreatstress,whichoftenleadstoadeclineinhealthandincreasedsusceptibilitytodiseases.Theadditionofmalicacidcanpromotethesecretionofdigestiveenzymes,improvethedigestionandabsorptionofnutrients,andenhancethehealthofthedigestivesystem.Atthesametime,malicacidcanregulatetheintestinalmicroflora,promotethegrowthofbeneficialbacteria,inhibitthegrowthofharmfulbacteria,andenhancetheimmunefunctionofweanedpiglets,thusreducingtheincidenceofdiarrheaandmortality.MolecularMechanismofMalicAcidinImprovingtheProductionPerformanceofWeanedPigletsStudieshaveshownthatthemolecularmechanismofmalicacidinimprovingtheproductionperformanceofweanedpigletsmainlyincludesthefollowingaspects:1.Promotethesecretionofdigestiveenzymes:Malicacidcanstimulatethesecretionofdigestiveenzymessuchasamylase,trypsin,chymotrypsin,andlipase,andincreasetheactivityofdigestiveenzymes,therebyimprovingthedigestionandabsorptionofnutrients.2.Regulatetheintestinalmicroflora:Malicacidcanregulatethecompositionofintestinalmicroflora,promotethegrowthofbeneficialbacteriasuchaslactobacillusandbifidobacterium,inhibitthegrowthofharmfulbacteriasuchasE.coliandSalmonella,andmaintainthebalanceofintestinalmicroflora.3.Improvethebarrierfunctionoftheintestinalmucosa:Malicacidcanincreasetheexpressionoftightjunctionproteinssuchasclaudin-1andoccludin,enhancethebarrierfunctionoftheintestinalmucosa,reducetheleakageofendotoxinandotherharmfulsubstances,andreducetheinflammationandimmuneresponseoftheintestinalmucosa.ConclusionandProspectInsummary,malicacidisanaturalorganicacidwithmanyphysiologicalfunctions,whichcanpromotethegrowthperformance,feedutilization,healthstatusandimmunefunctionofweanedpiglets.Themolecularmechanismofmalicacidinimprovingtheproductionperformanceofweanedpigletsmainlyincludespromotingthesecretionofdigestiveenzymes,regulatingtheintestinalmicroflora,andimprovingthebarrierfunctionoftheintestinalmucosa.However,therearestillmanyproblemsintheresearchofmalicacid,suchastheoptimaldosageofmalicacid,theinteractionofmalicacidwithotherfeedadditives,andthe